gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The mRNA vaccine primes HPV16-specific T cells; CD8+ cytotoxic T lymphocytes recognize HPV16 E7 peptides presented on MHC I of infected epithelial cells and induce apoptosis via perforin/granzyme (and Fas–FasL) pathways.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Viral oncoprotein; HPV type 16
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06273553
disease_id_num_tar_ref
2295
drug_id_num_tar_ref
6137