gene_symbol
CD1D
hgnc_id
HGNC:1637
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
iNKT cells recognize the CD1d–glycolipid complex via their invariant TCR and directly kill the presenting cell by releasing cytotoxic granules (perforin/granzyme) and engaging death-receptor pathways.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Restriction element for iNKT TCR recognizing glycolipid antigens
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06251973
disease_id_num_tar_ref
2321
drug_id_num_tar_ref
6191