gene_symbol
RAET1E
hgnc_id
HGNC:16793
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
AgenT-797 iNKT cells express NKG2D, which binds ULBP4 on target cells and triggers direct cytotoxic killing via perforin/granzyme release (with supportive Th1 cytokines).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Stress-induced NKG2D ligand
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06251973
disease_id_num_tar_ref
2321
drug_id_num_tar_ref
6191