gene_symbol
FCRL5
hgnc_id
HGNC:18508
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Bispecific antibody links CD3 on T cells to FCRH5 on target cells, forming an immune synapse and activating T-cell cytotoxicity (perforin/granzyme-mediated lysis) of FCRH5+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05927571
disease_id_num_tar_ref
2326
drug_id_num_tar_ref
6202