gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Bispecific binding to CD3 and BCMA cross-links T cells with BCMA+ cells, activating CTLs to form an immune synapse and kill targets via perforin/granzyme-mediated lysis/apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05927571
disease_id_num_tar_ref
2326
drug_id_num_tar_ref
6203