gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Elranatamab binds CD3 on T cells to activate and tether them to BCMA-expressing tumor cells; the activated T cells kill BCMA+ myeloma cells via cytolysis (perforin/granzyme), not CD3e+ T cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05927571
disease_id_num_tar_ref
2326
drug_id_num_tar_ref
6203