gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Blinatumomab binds CD3 on T cells to activate them; CD3E+ T cells act as effectors and kill CD19+ B cells via perforin/granzyme, not the CD3E+ cells themselves.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell receptor CD3 complex component
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06789107
disease_id_num_tar_ref
2329
drug_id_num_tar_ref
6212