gene_symbol
SSTR2
hgnc_id
HGNC:11331
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The radiolabeled somatostatin analog binds SSTR2, is internalized, and Lu-177 emits beta radiation that causes DNA damage (double-strand breaks), leading to death of SSTR2-positive cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05583708
disease_id_num_tar_ref
2346
drug_id_num_tar_ref
6253