gene_symbol
UNKNOWN
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Endogenous CMV-specific TCR on the engineered T cells recognizes CMV peptide–HLA class I complexes and triggers cytotoxic T-cell killing via perforin/granzyme (and related apoptosis pathways).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide–MHC complex recognition via endogenous CMV-specific TCR
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06252402
disease_id_num_tar_ref
2374
drug_id_num_tar_ref
6326