gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA-targeted CAR T cells recognize BCMA on plasmablasts/plasma cells and directly kill them via T-cell cytotoxicity (perforin/granzyme release and death-receptor–mediated apoptosis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Membrane receptor expressed on plasmablasts and long-lived plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06681337
disease_id_num_tar_ref
2380
drug_id_num_tar_ref
6343