gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD19 and engages Fcγ receptors on NK cells/macrophages to induce ADCC and ADCP, with additional direct apoptosis of CD19+ B cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Primary B-cell surface antigen target
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05583071
disease_id_num_tar_ref
2400
drug_id_num_tar_ref
6399