gene_symbol
UNKNOWN
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Tafasitamab binds CD19 on B cells and engages FcγRs on NK cells/macrophages to trigger ADCC/ADCP, killing CD19+ B cells; FcγR-expressing effector cells are not killed.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Fc-engineered IgG1 enhances FcγR engagement to drive ADCC/ADCP
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05583071
disease_id_num_tar_ref
2400
drug_id_num_tar_ref
6399