gene_symbol
MICA
hgnc_id
HGNC:7090
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
MICA is an NKG2D ligand; allogeneic Vγ9Vδ2 T cells bind MICA via NKG2D and directly kill target cells through perforin/granzyme release (and death receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Recognized by NKG2D on Vγ9Vδ2 T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05755854
disease_id_num_tar_ref
2418
drug_id_num_tar_ref
6455