gene_symbol
ULBP1
hgnc_id
HGNC:14893
binding_type
receptor ligand recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Vγ9Vδ2 T cells express NKG2D, which binds ULBP1 on target cells, triggering activation and direct killing via perforin/granzyme-mediated cytotoxicity (and death receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Recognized by NKG2D on Vγ9Vδ2 T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05755854
disease_id_num_tar_ref
2418
drug_id_num_tar_ref
6455