gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Native TCR recognition of the neoantigen–HLA class II complex on target cells triggers cytotoxic granule release (perforin/granzyme) leading to apoptosis.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
CD4+ TIL; MHC class II–restricted
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05724732
disease_id_num_tar_ref
2450
drug_id_num_tar_ref
6547