gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Infused neoantigen‑reactive T cells recognize the neoantigen–HLA class I complex via their native TCRs and kill target cells through perforin/granzyme-mediated cytotoxicity (and related CTL apoptotic pathways).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
CD8+ TCR recognition; MHC I–restricted peptide-MHC complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06432075
disease_id_num_tar_ref
2456
drug_id_num_tar_ref
6562