gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA-directed CAR T cells recognize BCMA on plasmablasts/plasma cells and induce T-cell cytolysis (perforin/granzyme-mediated apoptosis, with possible Fas–FasL contribution).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Also known as CD269; cell-surface receptor for BAFF/APRIL on plasmablasts and long-lived plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06519565
disease_id_num_tar_ref
2463
drug_id_num_tar_ref
6594