gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
CD3 on T cells is engaged to activate T cells; activated T cells kill CD20+ B cells via perforin/granzyme-mediated cytolysis. CD3-expressing T cells are not the targets of killing.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Target is the epsilon subunit within the CD3 T-cell receptor complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06097364
disease_id_num_tar_ref
2504
drug_id_num_tar_ref
6690