gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-engineered NK cells recognize BCMA on target cells and induce NK cytotoxic killing via perforin/granzyme release and death-receptor pathways, leading to apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Bispecific CAR target
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06594211
disease_id_num_tar_ref
233
drug_id_num_tar_ref
663