gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Binds CD3ε on T cells to activate/redirect them toward BCMA+ tumor cells; activated T cells kill BCMA-expressing cells via perforin/granzyme, not the CD3ε+ T cells themselves.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
TCR/CD3 complex component on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05646758
disease_id_num_tar_ref
2520
drug_id_num_tar_ref
6730