gene_symbol
HLA-A
hgnc_id
HGNC:4931
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Adoptively transferred neoantigen-specific T cells recognize the patient-specific peptide presented by HLA-A*11 via their native TCR and kill the target cell through perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
On
other_modifier
TCR recognition of patient-specific neoantigen bound to HLA-A*11; peptide–MHC class I complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06224049
disease_id_num_tar_ref
2522
drug_id_num_tar_ref
6734