gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells bind CD19 on target B-lineage cells and kill them via T-cell cytotoxicity—perforin/granzyme-mediated lysis and death-receptor (e.g., Fas) apoptosis, MHC-independent.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Surface antigen on B-lineage cells (B cells and plasmablasts); MHC-independent recognition
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06508346
disease_id_num_tar_ref
2536
drug_id_num_tar_ref
6770