gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA CAR engagement activates CAR T cells, which kill BCMA+ plasmablasts/plasma cells via perforin/granzyme-mediated cytolysis (and death-receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
dual-target CAR (BCMA and CD19)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06633042
disease_id_num_tar_ref
2539
drug_id_num_tar_ref
6789