gene_symbol
CD22
hgnc_id
HGNC:1643
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD22 CAR T cells bind CD22, become activated via CAR signaling, and kill target cells through perforin/granzyme-mediated cytolysis and death-receptor (e.g., Fas/FasL) apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen (Siglec-2)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06408194
disease_id_num_tar_ref
2544
drug_id_num_tar_ref
6802