gene_symbol
GPRC5D
hgnc_id
HGNC:13310
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Bispecific T‑cell engager binds GPRC5D on target cells and CD3 on T cells, forming an immune synapse that activates T cells to release perforin and granzymes, killing GPRC5D-positive cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06700395
disease_id_num_tar_ref
2549
drug_id_num_tar_ref
6814