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gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Binds CD3 on T cells to activate and bridge them to GPRC5D+ myeloma cells, which are then killed via perforin/granzyme release; CD3+ T cells are not targeted.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell receptor CD3 complex
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06700395
disease_id_num_tar_ref
2549
drug_id_num_tar_ref
6814