gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD20 mAb binds CD20 on B cells and induces complement-dependent cytotoxicity and Fc-mediated ADCC/phagocytosis, and can trigger apoptosis, depleting CD20+ cells.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Conformational epitope on the large extracellular loop of CD20 on pre-B and mature B cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06893328
disease_id_num_tar_ref
2556
drug_id_num_tar_ref
6826