gene_symbol
FOLH1
hgnc_id
HGNC:3788
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
An anti-PSMA antibody delivers actinium-225 to PSMA-expressing cells; emitted alpha particles induce localized DNA double-strand breaks, causing lethal damage to the target cells.
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface metalloenzyme on prostate cancer cells; extracellular domain recognized by antibody
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06549465
disease_id_num_tar_ref
2558
drug_id_num_tar_ref
6833