gene_symbol
KIT
hgnc_id
HGNC:6342
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD117 and blocks SCF–c‑Kit survival signaling, leading to apoptosis/depletion of KIT+ cells (with potential contribution from Fc-mediated effector functions).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Blocks SCF (KITLG) binding/signaling
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06736262
disease_id_num_tar_ref
2593
drug_id_num_tar_ref
6928