gene_symbol
DLL3
hgnc_id
HGNC:2909
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The DLL3×CD3 bispecific antibody bridges CD3+ T cells to DLL3+ cells, forming immune synapses and triggering T‑cell cytotoxicity (perforin/granzyme-mediated lysis) of DLL3-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
tumor-associated antigen (Notch pathway ligand)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06132113
disease_id_num_tar_ref
2630
drug_id_num_tar_ref
7014