gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA-specific CAR T cells recognize BCMA on target cells and, upon activation, kill them via perforin/granzyme-mediated cytolysis (apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Membrane-bound BCMA on malignant plasma cells; also known as TNFRSF17.
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06357754
disease_id_num_tar_ref
2633
drug_id_num_tar_ref
7023