gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Rituximab binds CD20 on B cells and induces killing via antibody-dependent cellular cytotoxicity (NK/macrophages via Fcγ receptors), complement-dependent cytotoxicity (C1q/MAC), and can trigger direct apoptosis upon CD20 ligation.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen (tetraspan membrane protein)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06062641
disease_id_num_tar_ref
2636
drug_id_num_tar_ref
7038