gene_symbol
RAET1G
hgnc_id
HGNC:16795
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NKG2D-CAR on NK-92 cells binds ULBP5 (an NKG2D ligand) on target cells, triggering NK activation and CAR signaling that induces perforin/granzyme-mediated cytotoxicity and tumor cell lysis/apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
stress-induced NKG2D ligand (also known as ULBP5)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05528341
disease_id_num_tar_ref
2638
drug_id_num_tar_ref
7043