gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR-NK cells bind CD19 on target cells and, upon CAR signaling, directly lyse them via NK degranulation (perforin/granzymes) and death-receptor apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CAR uses FMC63 scFv; NK-cell effector
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05336409
disease_id_num_tar_ref
2645
drug_id_num_tar_ref
7051