gene_symbol
IDO1
hgnc_id
HGNC:6059
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Vaccination induces IDO1-specific CD8+/CD4+ T cells that recognize IDO1-derived peptides on MHC and kill IDO1-expressing cells via CTL mechanisms (perforin/granzyme, Fas–FasL).
enzyme_product
On
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
21-mer long-peptide vaccine epitopes presented on MHC class I/II
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05843448
disease_id_num_tar_ref
2657
drug_id_num_tar_ref
7084