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gene_symbol
MUC1
hgnc_id
HGNC:7508
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
MUC1-specific T cells recognize MUC1 peptide–MHC on target cells and induce apoptosis via perforin/granzyme release (with possible Fas–FasL and cytokine-mediated effects).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Recognizes MUC1-derived peptide presented by MHC class I (peptide-MHC complex); MHC-restricted with patient-specific HLA
trial_id_tar_ref
nct_id_tar_ref
NCT06483048
disease_id_num_tar_ref
2663
drug_id_num_tar_ref
7098