gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Vaccine peptides are presented by APCs to prime/expand neoantigen-specific CD8+ T cells, which then recognize neoantigen–HLA on tumor cells and kill them via perforin/granzyme and apoptotic pathways.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Multiple patient-tailored peptides derived from tumor somatic mutations; designed for HLA-restricted presentation
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06314087
disease_id_num_tar_ref
2709
drug_id_num_tar_ref
7215