gene_symbol
CD3G
hgnc_id
HGNC:1675
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-thymocyte globulin binds the CD3 complex (including CD3γ) on T cells and induces complement-dependent lysis and Fc receptor–mediated ADCC/phagocytosis, depleting the target cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
TCR-CD3 complex component
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05902416
disease_id_num_tar_ref
2727
drug_id_num_tar_ref
7257