gene_symbol
IL2RA
hgnc_id
HGNC:6008
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Polyclonal antibodies in ATG bind CD25 (and other T‑cell antigens) on T cells, triggering complement-dependent lysis and Fc-mediated ADCC/phagocytosis to deplete CD25+ T cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Activation marker on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05902416
disease_id_num_tar_ref
2727
drug_id_num_tar_ref
7257