gene_symbol
PTPRC
hgnc_id
HGNC:9666
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ATG binds CD45 on T cells and triggers complement-dependent cytotoxicity and Fc-mediated ADCC/phagocytosis, leading to lysis and depletion of the target cells.
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Receptor-type tyrosine phosphatase
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05902416
disease_id_num_tar_ref
2727
drug_id_num_tar_ref
7257