gene_symbol
ITGB1
hgnc_id
HGNC:6153
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-thymocyte globulin contains antibodies that bind CD29 on T cells, triggering complement-dependent cytotoxicity and Fc-mediated ADCC/phagocytosis to deplete those cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Integrin; adhesion/costimulation
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05902416
disease_id_num_tar_ref
2727
drug_id_num_tar_ref
7257