gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Bispecific BCMA×CD3 engagement cross-links T cells to BCMA-expressing cells, forming an immune synapse and triggering perforin/granzyme-mediated T-cell cytotoxicity leading to apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface receptor on malignant plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06285318
disease_id_num_tar_ref
2772
drug_id_num_tar_ref
7402