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gene_symbol
EGFR
hgnc_id
HGNC:3236
binding_type
other
cytotoxicity
NO
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Lazertinib is a mutant‑selective EGFR tyrosine kinase inhibitor with minimal activity on wild‑type EGFR, so wtEGFR-expressing cells are not directly inhibited or killed.
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Reduced activity vs wild-type EGFR
trial_id_tar_ref
drug_id_tar_ref
nct_id_tar_ref
NCT05299125
disease_id_num_tar_ref
2793
drug_id_num_tar_ref
7460