gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR T cells bind CD19 on target B cells, become activated, and kill them via T-cell cytotoxic mechanisms (perforin/granzyme-mediated lysis and apoptosis; Fas/FasL).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen; HLA-independent CAR recognition
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06256484
disease_id_num_tar_ref
2808
drug_id_num_tar_ref
7498