gene_symbol
FOLH1
hgnc_id
HGNC:3788
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
PSMA-targeted CAR T cells recognize PSMA on tumor cells and kill them via T-cell effector functions, including perforin/granzyme-mediated cytolysis and death-receptor signaling.
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface tumor antigen; recognized by humanized J591-derived scFv CAR with CD2 costimulatory domain
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06046040
disease_id_num_tar_ref
2830
drug_id_num_tar_ref
7552