gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA×CD3 bispecific antibody links T cells to BCMA+ cells, triggering CD3-mediated activation and immune-synapse formation, leading to perforin/granzyme-dependent lysis and apoptosis of the target cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface receptor on malignant plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06282978
disease_id_num_tar_ref
2843
drug_id_num_tar_ref
7588