gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Blinatumomab binds CD3 on T cells and CD19 on B cells to redirect T-cell perforin/granzyme killing toward CD19+ cells; CD3ε-expressing T cells are effectors, not the killed targets.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
TCR-CD3 complex component on T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06061094
disease_id_num_tar_ref
2865
drug_id_num_tar_ref
7658