gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Elranatamab binds CD3 on T cells to recruit/activate them and bridge them to BCMA+ myeloma cells; the activated T cells kill the BCMA-expressing tumor cells (via perforin/granzyme), not the CD3+ T cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CD3 complex on T cells; specific subunit not specified
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06504524
disease_id_num_tar_ref
2878
drug_id_num_tar_ref
7709