gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Binding to CD3 activates T cells; the activated T cells kill CD20+ B cells via immune-synapse–mediated perforin/granzyme release. CD3+ T cells are not the cells killed.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell receptor CD3 complex component
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06656234
disease_id_num_tar_ref
252
drug_id_num_tar_ref
711