gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
NK cells coated with a CD19/CD20 bispecific IgG bind CD20 on B cells, form an immune synapse, and kill via NK degranulation (perforin/granzyme) and Fc-mediated ADCC.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06693973
disease_id_num_tar_ref
2893
drug_id_num_tar_ref
7755